5 herbal supplements that can damage the liver

A study in JAMA Network Open reveals a rise in drug-induced liver injuries associated with herbal supplements like green tea extract, turmeric, ashwagandha, black cohosh, and red yeast rice. The report stresses the need for medical consultation before using these products to avoid severe liver damage.
5 herbal supplements that can damage the liver
Herbal remedies are gaining much popularity among people across the world considering they are largely seen as free of side-effects. Green tea, turmeric, ashwagandha are all healthy additions to your diet and one often doesn't think twice before consuming them for boosting immunity and strengthening health. However, relying blindly on age-old wisdom, without consultation from your health experts could damage your liver.
1x1 polls

The study, published in JAMA Network Open, found that drug-induced liver injury, tied with products like green tea extract, turmeric or curcumin, ashwagandha, black cohosh, red yeast rice, and Garcinia cambogia, has been seeing a rise in the US, highlighting the need to dangers of indiscriminate use of the herbal supplements, partly due to weak laws around regulation of dietary supplement industry. Nearly 5% of American adults might be taking one or more of these products, per the new report.
There are many benefits of the above-mentioned herbs if taken in moderation, but many people tend to over-do their consumption, the risk of injury to internal organs can increase.
Here are 5 herbs that could be harming your liver silently, as per the above study:

1. Turmeric

Turmeric is a popular herb which derived from the roots of the plant Curcuma longa and is widely used in culinary preparations. Turmeric is part of many traditional Ayurvedic formulations due to its main beneficial component curcumin which can offer a range of benefits from controlling inflammation, improving antioxidant activities, heart health and reducing risk of cancer. However, consuming turmeric in large quantities is linked to
liver damage and increase the risk of kidney stone formation. Cases of acute hepatic injury, liver failure, and liver damage have been reported with consuming excessive turmeric. While using turmeric while cooking in small amounts is perfectly healthy, taking supplements or shots should be strictly on recommendation by a medical expert.

2. Ashwagandha

ashwagandha

Ashwagandha, an Ayurvedic herb, is derived from Withania somnifera root extract, an evergreen shrub that is endemic to India and Southeast Asia. It is also called 'Indian ginseng' and is known to boost brain health and lower anti-inflammatory activities. It is used to treat stress, fatigue, pain, skin diseases, diabetes, arthritis and epilepsy. An energy tonic, it also helps reduce fatigue and counteract the effects of aging. Cases of liver injury in people who took commercial herbal products that are labelled as containing ashwagandha, have been observed, according to Livertox. The liver injury could also be due to impurities in the ashwagandha, higher concentrations of extracts, or taking more than the recommended dose.

3. Green tea extract


Green tea's many benefits have been highlighted in many studies as the herbal tea is known for protection against cancer, heart disease, obesity and type 2 diabetes. However, liver damage linked to green tea extract has been reported in many cases, cautioning the green tea lovers to exercise caution while consuming it in large quantities. Green tea extract is found in a number of herbal and dietary supplements. Green tea extract or having large amounts of green tea have in some cases lead to acute liver failure or need for urgent liver transplantation or death.
US National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) warns that green tea extract has been linked with liver damage so severe as to require transplant or lead to death.

4. Black cohosh


Black cohosh, a popular herbal remedy used for menopausal symptoms, has been linked to liver injuries such as jaundice, hepatitis, and autoimmune hepatitis. The adverse effects can appear between 2 to 12 weeks of consumption, while in some it has been reported 48 weeks after use. The U.S. Pharmacopeia advises individuals with liver disorders to avoid black cohosh, and recommends that anyone experiencing signs of liver trouble discontinue its use and seek medical advice. Published literature suggests that large doses of black cohosh might be associated with gastrointestinal irritation, headache, dizziness, and vomiting.

5. Red yeast rice

Red yeast rice is the product of rice fermented with a type of yeast called Monascus purpureus. It has monacolin K, the same active ingredient found in the prescription drug lovastatin, which is known to cause liver damage. However, the concentration of monacolin K in red yeast rice is unregulated, varying significantly from 0.09 to 10.94 mg per daily dose, which makes its effects unpredictable. This supplement has been linked to severe adverse reactions, like acute liver injury, and recovery can take months after discontinuation. Due to these risks, individuals with liver disease or those at risk for liver problems should avoid red yeast rice.
Herbal supplements can elevate your health and improve well-being but in larger quantities, it can spell digestive trouble and lead to symptoms like nausea, vomiting, and diarrhea. Some of these supplements can also cause headache, muscle or joint pain, or lead to sleeplessness. One may be careful that they do not interact with the current medications you are taking.

5 Health benefits of eating green chilies with your meals


To use herbal supplements correctly and ensure safety against interfering with drugs, always seek a doctor's guidance first. Always follow the recommended dosage indicated in the supplement's label, since any intake over or under this measure may have bad effects on the body. Take the supplement regularly and at about the same time every day to have improved effects, and take it as prescribed, either with or without food.
Choose high-quality, reputable brands that have the products third-party tested for purity. Monitor your body's reaction: if you experience any side effects, stop use immediately. Periodically evaluate your supplement regimen as part of your overall health plan.
author
About the Author
TOI Lifestyle Desk

The TOI Lifestyle Desk is a dynamic team of dedicated journalists who, with unwavering passion and commitment, sift through the pulse of the nation to curate a vibrant tapestry of lifestyle news for The Times of India readers. At the TOI Lifestyle Desk, we go beyond the obvious, delving into the extraordinary. Consider us your lifestyle companion, providing a daily dose of inspiration and information. Whether you're seeking the latest fashion trends, travel escapades, culinary delights, or wellness tips, the TOI Lifestyle Desk is your one-stop destination for an enriching lifestyle experience.

End of Article
FOLLOW US ON SOCIAL MEDIA